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Name
Prof Frederic Leusch

Location
Griffith University Gold Coast Campus, Parklands Dr, Southport, Qld 4222

Phone
+61 7 5552 7832

E-mail
f.leusch@griffith.edu.au

Links
Twitter @fredleusch
Web: http://www.leusch.info
ResearcherID: http://www.researcherid.com/rid/A-2806-2011
ResearchGate: http://www.researchgate.net/profile/Frederic_Leusch
Griffith Experts: https://experts.griffith.edu.au/18672-frederic-leusch

Short bio
Fred is Professor in the School of Environment and Science at Griffith University, where he teaches biology and environmental toxicology. Fred also leads the ARI Toxicology Research Group at the Australian Rivers Institute on the Gold Coast. His current research focuses on endocrine disruption in the Australian environment, validating ethical alternatives to animal toxicity testing, developing novel bioassays for water quality assessment, and the application of systems biology methods to evaluate exposure to environmental pollutants. He serves on various national and international committees on issues related to the significance of trace organic pollutants to drinking and recycled water quality as well as development and validation of animal alternatives for toxicity testing. He is currently chairing the Water Quality Advisory Committee of the National Health and Medical Research Council, which provides advice to the NHMRC on the Australian Drinking Water Guidelines.

Position
Professor, Australian Rivers Institute and School of Environment and Science

Education
PhD (2005) in Environmental Toxicology from Lincoln University, New Zealand
MSc (2002) in Environmental Science from the University of New Brunswick, Canada
BSc (1998) in Biology from McGill University

HDR supervision

  • Taylor Wilde (Hons) – Optimization of Reporter Gene Assays for Water Quality Monitoring, current
  • Tharindu Dampe Acharige (MSc) – Occurrence of Micro-plastic in Marine Aquatic Fauna, current
  • Hafiz Hosen (PhD) – Linking Humpback Whale Chemical Exposure To Effect: Taxon Specific In-vitro Toxicity Assessment, current
  • Matt Johnson (PhD) – Development and validation of a new suite of in vitro bioassays for environmental monitoring, current
  • Kushani Perera (PhD) – Assessing the risk of airborne microplastics, current [see here]
  • Sana Ajaz (PhD) – Assessing biofiltration for the removal of PPCPs and their TPs from drinking water, current [see here]
  • Hsuan-Cheng Lu (PhD) – Microplastic pollution in urban wetlands and associated trophic effects in wetland biota, current [see here]
  • Arthur Barraza (PhD) – Assessing toxicology of sea turtles, current [see here]
  • Julia Smith (PhD) – Assessing the Toxicological Status of Sharks as Apex Predators in the Australian Marine Ecosystem, current [see here]
  • Gulsah Dogruer (PhD) – Assessing the impact of chemical exposure on the health of endangered sea turtles through toxicokinetics and toxicodynamics, current [see here]
  • Steph Chaousis (PhD) – The use of non-targeted proteomics and in vitro bioassays as a non-destructive approach towards the development of biomarkers of contaminant exposure in threatened marine wildlife, 2015-2019
  • Kimberly Finlayson (PhD) – Development, validation and application of an in vitro toxicological model for sea turtles, 2015-2018
  • Shima Ziajahromi (PhD) – Identification and quantification of microplastics in wastewater treatment plant effluent, 2014-2018
  • Erin Wallace (PhD) – Investigating life history stages and methods to interrupt the life cycle, and suppress offspring production, in the Queensland fruit fly (Bactrocera tryoni), 2016-2017
  • Eric Prochazka (PhD) –
  • Phil Scott (PhD) – Investigation of endocrine disruption in Australian aquatic environments, 2010-2014

Grants

  1. Global Water Research Coalition, Effect-Based Monitoring in Water Safety Planning, 2019-2022
  2. ARC, Oyster biomonitor for endocrine disrupting chemicals, 2020-2023
  3. Advance Queensland, Risks of microplastics in biosolids to soils and agro-ecosystems, 2020-2024
  4. Water Research Australia, Emerging contaminants risk framework (ECHIDNA), 2020-2022
  5. ARC, Saving Nemo: Reducing animal use in toxicity assessments of wastewater, 2019-2022.
  6. NZ Ministry of Business, Innovation and Employment, Emerging organic contaminants – managing risk for a safer NZ environment and economy, 2018-2022.
  7. ARC, Will catchment revegetation cause unintended consequences for waterways? 2016-2018.
  8. ARC, Can wastewater treatment increase the ecotoxicity of chiral chemicals? (DP17100357), 2017-2019.
  9. Sea World Research and Rescue Foundation, Establishment of Australia’s first national marine wildlife cell culture bank, 2018.
  10. CSIRO Future Science Fellowships in Synthetic Biology, Tissue engineered jellyfish-like pseudo-organisms for aquatic detoxification, 2017-2020.
  11. Water Research Australia, Development of a suite of cell-based bioassays for a more ethical and cost-effective direct toxicity assessment of wastewaters – stage 1, 2016-2017.
  12. Water Research Australia, Robust wastewater discharge assessment – a risk-based approach, 2015-2016.
  13. Global Water Research Coalition / Water Research Australia, EDC Toolbox II – Analysing more than just estrogenic activity in environmental waters: androgenic, progestagenic, glucocorticoid, RXR, PPAR and thyroid activity, 2014-2016.
  14. NHMRC-EU Collaborative Research Grants, SOLUTIONS for present and future emerging pollutants in land and water resources management (APP1074775), 2014-2016.
  15. Australian Water Recycling Centre of Excellence, NatVal 2.2 – Development of a National validation framework for water recycling (Subproject 4), 2013-2015.
  16. Water Research Australia, Identify and assess the water quality risks from extreme events, 2013-2015.
  17. Water Research Australia, Assessing the human health risks associated with micropollutants in stormwater intended for beneficial reuse, 2013-2015.
  18. National Environment Science Program – Tropical Water Quality Hub, Identification and prioritization of emerging contaminants in the Great Barrier Reef lagoon, 2015.
  19. Water Research Foundation / Water Research Australia, Transformation chemistry of EDCs/PPCPs resulting from the disinfection of drinking water, 2012-2014.
  20. Water Quality Research Australia, Stormwater quality and reuse risk assessment, 2011-2014.
  21. ARC Linkage, Investigation of endocrine disruption in Australian aquatic environments (LP100100163), 2010-2014.
  22. Australian Water Recycling Centre of Excellence, Stream 1.2: Biomonitoring (part of “Reclaimed water is viewed as an acceptable alternative for augmenting drinking water supplies”), 2011-2014.
  23. Global Water Research Coalition, Tools for analysing androgenic, thyroid, glucocorticoid and progestagenic activity in environmental waters: Stage 1 literature review, 2012.
  24. Water Reuse Research Foundation (WRRF), Development of bio-analytical techniques to assess the potential health impacts of recycled water, 2011-2013.
  25. Urban Water Security Research Alliance, Bioassays and risk communication, 2010-2012.
  26. Urban Water Security Research Alliance, DBP formation in alternate water sources, 2010-2012.
  27. Water Quality Research Australia, Safety of recycled water for end users determined by a mouse in vivo multigenerational study – Phase I, 2010.

Books

  1. Escher BE, Neale PA and Leusch FDL (2021). Bioanalytical tools in water quality assessment – Second Edition. IWA Publishing, London, UK. 462pp. ISBN 978-1-789061-97-0 [available here]
  2. Leusch FDL, Sacher F, Scheurer M, Hebert A and Schriks M (2017) Bioanalytical tools to analyse hormonal activity in environmental waters. Global Water Research Coalition, UK. 237pp. ISBN 978-1-921732-40-9
  3. Leusch F, Hebert A and Schriks M (2013). Bioanalytical tools to analyse hormonal activity in environmental waters. Global Water Research Coalition, UK. 180pp. ISBN 978-90-77622-29-2
  4. enHealth (2012). The role of toxicity testing in identifying toxic substances in water. enHealth, Department of Health and Ageing, Canberra, ACT, Australia. 33pp. ISBN 978-1-74241-439-3 [available FREE here]
  5. Escher BE and Leusch FDL (2012). Bioanalytical tools in water quality assessment. With contributions by Chapman HF and Poulsen A. IWA Publishing, London, UK. 253pp. ISBN 978-1-843393-68-9 [available here, but see 2nd edition above]
  6. GWRC (2008). Tools to detect estrogenicity in environmental waters – Final report. Prepared by Leusch FDL. Global Water Research Coalition (GWRC) / Water Environment Research Foundation (WERF), Alexandria, VA, USA. 74pp.
  7. GWRC (2006). In vitro bioassays to detect estrogenic activity in environmental waters – A literature review. Prepared by Leusch FDL. Global Water Research Coalition (GWRC) / Water Environment Research Foundation (WERF), Alexandria, VA, USA. 76pp.
  8. Leusch FDL (2004) Estrogenic and androgenic potential of municipal sewage in Australia and New Zealand. PhD thesis (Gooneratne SR, Tremblay LA, and Chapman HF, supervisors; Ling N, and Denslow N, eds). Lincoln University, Lincoln, New Zealand. 126pp. [available FREE here]
  9. Leusch FDL (2001). Mechanisms of action of phytosterols on goldfish (Carassius auratus) gonadal steroidogenesis. Msc Thesis (MacLatchy DL, Benfey T, and Chopin T, supervisors; Frego K, and Laforce R, eds), University of New Brunswick, NB, Canada. 160pp. [available FREE here]

Book Chapters

  1. Denslow ND, Maruya KA and Leusch FDL (2016). Bioanalytical approaches in assessing transformation products. Chapter 4 in Drewes JE and Letzel T (Ed.), Assessing transformation products of chemicals by non-target and suspect screening: Strategies and workflows Volume 2, pp. 73-87. ACS Symposium Series Vol 1242, American Chemical Society, Washington DC, USA.
  2. Chapman HF, Leusch FDL and Tan BLL (2008). Risk management of chemicals in recycled water. Chapter 5 in Purified recycled water for drinking: The technical issues. Queensland Water Commission, Brisbane, QLD, Australia. 273pp.
  3. Chapman HF, Leusch FDL and Tan BLL (2007). Endocrine disruptors. Chapter 1 in Occasional Paper 8: Chemicals of concern in wastewater treatment plant effluent: State of the science in Australia. Cooperative Research Centre for Water Quality and Treatment. Adelaide, SA, Australia. 82 pp.

Journal Articles

  1. Johnson, M., Finlayson, K., Shelper, T., van de Merwe, J.P., Leusch, F.D.L. (2022) Optimisation of an automated high-throughput micronucleus (HiTMiN) assay to measure genotoxicity of environmental contaminants, Chemosphere 298: 134349
  2. Islam, R., Melvin, S.D., Kit Yu, R.M., O’Connor, W.A., Anh Tran, T.K., Andrew-Priestley, M., Leusch, F.D.L., MacFarlane, G.R. (2022) Estrogenic mixtures induce alterations in lipidomic profiles in the gonads of female oysters, Chemosphere 291: 132997
  3. Ziajahromi, S., Leusch, F.D.L. (2022) Systematic assessment of data quality and quality assurance/quality control (QA/QC) of current research on microplastics in biosolids and agricultural soils, Environ Poll 294: 118629
  4. Nguyen, A.Q., Nguyen, L.N., McDonald, J.A., Nhigme, L.D., Leusch, F.D.L., Neale, P.A., Khan, S.J. (2022) Chiral inversion of 2-arylpropionoic acid (2-APA) enantiomers during simulated biological wastewater treatment, Water Res 209: 117871
  5. Papa, M., Dogruer, G., Bailey, D., Leusch, F.D.L. (2022) Anaerobic digestion of sewage sludge has no effect on glucocorticoid and anti-progestagenic activity but increases estrogenicity three-fold, Chemosphere 286: 131753
  6. Barraza, A.D., Finlayson, K.A., Leusch, F.D.L., van de Merwe, J.P. (2021) Systematic review of reptile reproductive toxicology to inform future research directions on endangered or threatened species, such as sea turtles, Environ Poll 286: 117470
  7. Leusch, F.D.L., Ziajahromi, S. (2021) Converting mg/L to Particles/L: Reconciling the Occurrence and Toxicity Literature on Microplastics, Environ Sci Technol 55(17): 11470-11472 [open access available here]
  8. Franklin, H.M., Doederer, K., Neale, P.A., Hayton, J.B., Fisher, P., Maxwell, P., Carroll, A.R., Burford, M.A., Leusch, F.D.L. (2021) Terrestrial dissolved organic matter source affects disinfection by-product formation during water treatment and subsequent toxicity, Environ Poll 283: 117232
  9. Lu, H.-C., Ziajahromi, S., Neale, P.A., Leusch, F.D.L. (2021) A systematic review of freshwater microplastics in water and sediments: Recommendations for harmonisation to enhance future study comparisons, Sci Total Environ 781: 146693
  10. Finlayson, K.A., Leusch, F.D.L., Villa, C.A., Limpus, C.J., van de Merwe, J.P. (2021) Combining analytical and in vitro techniques for comprehensive assessments of chemical exposure and effect in green sea turtles (Chelonia mydas), Chemosphere 274: 129752
  11. Leusch, F.D.L., Hollert, H., Holmes, G. (2021) Editorial – Virtual special issue (VSI) green turtles as silent sentinels of pollution in the Great Barrier Reef – Rivers to Reef to Turtles project, Sci Total Environ 757: 144188
  12. Islam, R., Melvin, S.D., Yu, R.M.K., O’Connor, W.A., Tran, T.K.A., Andrew-Priestley, M., Leusch, F.D.L., MacFarlane, G.R. (2021) Exposure to estrogenic mixtures results in tissue-specific alterations to the metabolome of oysters, Aquat Toxicol 231: 105722
  13. Chaousis, S., Leusch, F.D.L., Nouwens, A., Melvin, S.D., van de Merwe, J.P. (2021) Changes in global protein expression in sea turtle cells exposed to common contaminants indicates new biomarkers of chemical exposure, Sci Total Environ 751: 141680
  14. Ziajahromi, S., Neale, P.A., Telles Silveira, I., Chua, A., Leusch, F.D.L. (2021) An audit of microplastic abundance throughout three Australian wastewater treatment plants, Chemosphere 263: 128294
  15. Islam, R., Kit Yu, R.M., O’Connor, W.A., Anh Tran, T.K., Andrew-Priestley, M., Leusch, F.D.L., MacFarlane, G.R. (2020) Parental exposure to the synthetic estrogen 17α-ethinylestradiol (EE2) affects offspring development in the Sydney rock oyster, Saccostrea glomerata, Environ Pollut 266: 114994
  16. Neale, P.A., Grimaldi, M., Boulahtouf, A., Leusch, F.D.L., Balaguer, P. (2020) Assessing species-specific differences for nuclear receptor activation for environmental water extracts, Water Res 185: 116247
  17. Weijs, L., Covaci, A., Stevenson, G., Kemper, C., Tomo, I., Leusch, F. (2020) Concentrations of some legacy pollutants have increased in South Australian bottlenose dolphins from 1989 to 2014, Environ Res 189: 109834
  18. Singh, A., Eftekhari, E., Scott, J., Kaur, J., Yambem, S., Leusch, F., Wellings, R., Gould, T., Ostrikov, K., Sonar, P., Li, Q. (2020) Carbon dots derived from human hair for ppb level chloroform sensing in water, Sustain Mat Technol 25: e00159
  19. Kroon, F.J., Berry, K.L.E., Brinkman, D.L., Kookana, R., Leusch, F.D.L., Melvin, S.D., Neale, P.A., Negri, A.P., Puotinen, M., Tsang, J.J., van de Merwe, J.P., Williams, M. (2020) Sources, presence and potential effects of contaminants of emerging concern in the marine environments of the Great Barrier Reef and Torres Strait, Australia, Sci Total Environ 719: 135140
  20. Ziajahromi, S., Drapper, D., Hornbuckle, A., Rintoul, L., Leusch, F.D.L. (2020) Microplastic pollution in a stormwater floating treatment wetland: Detection of tyre particles in sediment, Sci Total Environ 713: 136356
  21. Asif, M.B., Van De Merwe, J.P., Leusch, F.D.L., Pramanik, B.K., Price, W.E., Hai, F.I. (2020) Elucidating the performance of an integrated laccase- and persulfate-assisted process for degradation of trace organic contaminants (TrOCs), Environ Sci: Water Res Technol, 6(4): 1069-1082
  22. Leusch, F.D.L., Khan, S.J., Deere, D., Cunliffe, D., Neale, P.A., Humpage, A. (2020) Deriving safe short-term chemical exposure values (STEV) for drinking water, Reg Toxicol Pharm 110: 104545
  23. Neale, P.A., Branch, A., Khan, S.J., Leusch, F.D.L. (2019) Evaluating the enantiospecific differences of non-steroidal anti-inflammatory drugs (NSAIDs) using an ecotoxicity bioassay test battery, Sci Total Environ 694: 133659
  24. Alharbi SK, Nghiem LD, van de Merwe JP, Leusch FDL, Asif MB, Hai FI, Price WE (2019) Degradation of diclofenac, trimethoprim, carbamazepine, and sulfamethoxazole by laccase from Trametes versicolor: Transformation products and toxicity of treated effluent. Biocatal Biotransform 37(6): 399-408
  25. Gaw, S., Harford, A., Pettigrove, V., Sevicke-Jones, G., Manning, T., Ataria, J., Cresswell, T., Dafforn, K.A., Leusch, F.D.L., Moggridge, B., Cameron, M., Chapman, J., Coates, G., Colville, A., Death, C., Hageman, K., Hassell, K., Hoak, M., Gadd, J., Jolley, D.F., Karami, A., Kotzakoulakis, K., Lim, R., McRae, N., Metzeling, L., Mooney, T., Myers, J., Pearson, A., Saaristo, M., Sharley, D., Stuthe, J., Sutherland, O., Thomas, O., Tremblay, L., Wood, W., Boxall, A.B.A., Rudd, M.A., Brooks, B.W. (2019) Towards Sustainable Environmental Quality: Priority Research Questions for the Australasian Region of Oceania, Integr Environ Assess Manag 15(6): 917-935
  26. Asif MB, Fida Z, Tufail A, van de Merwe JP, Leusch FDL, Pramanik BK, Price WE, Hai FI (2019) Persulfate oxidation-assisted membrane distillation process for micropollutant degradation and membrane fouling control. Separation and Purification Technology 222: 321-331
  27. Weijs L, Leusch F, Covaci A, 2019. Concentrations of legacy persistent organic pollutants and naturally produced MeO-PBDEs in dugongs (Dugong dugon) from Moreton Bay, Australia. Chemosphere, 229, 500-508.
  28. Ziajahromi, S., Kumar, A., Neale, P.A., Leusch, F.D.L. (2019) Effects of polyethylene microplastics on the acute toxicity of a synthetic pyrethroid to midge larvae (Chironomus tepperi) in synthetic and river water, Sci. Total Environ. 671: 971-975
  29. Neale, P.A., Leusch, F.D.L. (2019) Assessing the role of different dissolved organic carbon and bromide concentrations for disinfection by-product formation using chemical analysis and bioanalysis, Environ. Sci. Pollut. Res. 26: 17100-17109
  30. Finlayson KA, Leusch FDL, Limpus CJ, van de Merwe JP (2019) Towards the development of standardised sea turtle primary cell cultures for toxicity testing. Ecotoxicology and Environmental Safety 173: 63-70
  31. Finlayson KA, Leusch FDL, van de Merwe JP (2019) Cytotoxicity of organic and inorganic compounds to primary cell cultures established from internal tissues of Chelonia mydas. Science of the Total Environment 664: 958-967
  32. Tran TKA, Yu RMK, Islam R, Nguyen THT, Bui TLH, Kong RYC, O’Connor WA, Leusch FDL, Andrew-Priestley M, MacFarlane GR (2019) The utility of vitellogenin as a biomarker of estrogenic endocrine disrupting chemicals in molluscs. Environmental Pollution 248: 1067-1078
  33. Leusch, F.D.L., Neale, P.A., Busetti, F., Card, M., Humpage, A., Orbell, J.D., Ridgway, H., Stewart, M.B., van de Merwe, J.P., Escher, B.I. (2019) Transformation of endocrine disrupting chemicals, pharmaceutical and personal care products during drinking water disinfection, Sci. Total Environ. 657: 1480-1490
  34. Finlayson KA, Leusch FDL, van de Merwe JP (2019) Primary green turtle (Chelonia mydas) skin fibroblasts as an in vitro model for assessing genotoxicity and oxidative stress. Aquatic Toxicology 207: 13-18
  35. Procházka, E., Melvin, S.D., Escher, B.I., Plewa, M.J., Leusch, F.D.L. (2019) Global transcriptional analysis of nontransformed human intestinal epithelial cells (FHs 74 Int) after exposure to selected drinking water disinfection by-products, Environ Health Perspect 127(11): 117006
  36. Daniels KD, VanDervort D, Wu S, Leusch FDL, van de Merwe JP, Jia A, Snyder SA (2018) Downstream trends of in vitro bioassay responses in a wastewater effluent-dominated river. Chemosphere 212: 182-192
  37. Neale, P.A., Leusch, F.D.L., Escher, B.I. (2018) What is driving the NF-κB response in environmental water extracts? Chemosphere 210: 645-652
  38. Watson K, Farré MJ, Leusch FDL and Knight N (2018) Using fluorescence-parallel factor analysis for assessing disinfection by-product formation and natural organic matter removal efficiency in secondary treated synthetic drinking waters. Science of the Total Environment
  39. Leusch FDL, Neale PA, Arnal C, Aneck-Hahn NH, Balaguer P, Bruchet A, Escher BI, Esperanza M, Grimaldi M, Leroy G, Scheurer M, Schlichting R, Schriks M and Hebert A (2018) Analysis of endocrine activity in drinking water, surface water and treated wastewater from six countries. Water Research 139: 10-18.
  40. Melvin SD, Leusch FDL and Carroll AR (2018) Metabolite profiles of striped marsh frog (Limnodynastes peronii) larvae exposed to the anti-androgenic fungicides vinclozolin and propiconazole are consistent with altered steroidogenesis and oxidative stress. Aquatic Toxicology 199: 232-239.
  41. van de Merwe JP, Neale PA, Melvin SD and Leusch FDL (2018) In vitro bioassays reveal that additives are significant contributors to the toxicity of commercial household pesticides. Aquatic Toxicology 199: 263-268.
  42. Melvin SD, Jones OAH, Carroll AR and Leusch FDL (2018) 1H NMR-based metabolomics reveals interactive effects between the carrier solvent methanol and a pharmaceutical mixture in an amphibian developmental bioassay with Limnodynastes peronei. Chemosphere 199: 372-381.
  43. Ziajahromi S, Kumar A, Neale PA and Leusch FDL (2018) Environmentally relevant concentrations of polyethylene microplastics negatively impact the survival, growth and emergence of sediment-dwelling invertebrates. Environmental Pollution 236: 425-431.
  44. Chaousis S, Leusch FDL and van de Merwe JP (2018) Charting a path towards non-destructive biomarkers in threatened wildlife: A systematic quantitative literature review. Environmental Pollution 234: 59-70
  45. Scott PD, Coleman HM, Khan S, Lim R, McDonald JA, Mondon J, Neale PA, Prochazka E, Tremblay LA, Warne MS and Leusch FDL (2018). Histopathology, vitellogenin and chemical body burden in mosquitofish (Gambusia holbrooki) sampled from six river sites receiving a gradient of stressors. Science of the Total Environment 616-617: 1638-1648
  46. Asif MB, Hai FI, Kang J, van de Merwe JP, Leusch FDL, Price WE and Nghiem LD (2018) Biocatalytic degradation of pharmaceuticals, personal care products, industrial chemicals, steroid hormones and pesticides in a membrane distillation-enzymatic bioreactor. Bioresource Technology 247: 528-536
  47. Leusch FDL, Aneck-Hahn NH, Cavanagh JAE., Du Pasquier D, Hamers T, Hebert A, Neale PA, Scheurer M, Simmons SO and Schriks M (2018) Comparison of in vitro and in vivo bioassays to measure thyroid hormone disrupting activity in water extracts. Chemosphere 191: 868-875
  48. Ziajahromi S, Kumar A, Neale PA and Leusch FDL (2017) Impact of microplastic beads and fibers on waterflea (Ceriodaphnia dubia) survival, growth, and reproduction: Implications of single and mixture exposures. Environmental Science and Technology 51: 13397-13406
  49. Alharbi SK, Kang J, Nghiem LD, van de Merwe JP, Leusch FDL and Price WE (2017) Photolysis and UV/H2O2 of diclofenac, sulfamethoxazole, carbamazepine, and trimethoprim: Identification of their major degradation products by ESI-LC-MS and assessment of the toxicity of reaction mixtures. Process Safety and Environmental Protection 112: 222-234
  50. Neale PA, Achard MES, Escher BI and Leusch FDL (2017) Exploring the oxidative stress response mechanism triggered by environmental water samples. Environmental Science: Processes and Impacts 19 (9): 1126-1133
  51. Boehler S, Strecker R, Heinrich P, Prochazka E, Northcott GL, Ataria JM, Leusch FDL, Braunbeck T and Tremblay LA (2017) Assessment of urban stream sediment pollutants entering estuaries using chemical analysis and multiple bioassays to characterise biological activities. Science of the Total Environment 593-594: 498-507
  52. Asif MB, Hai FI, Kang J, van de Merwe JP, Leusch FDL, Yamamoto K, Price WE and Nghiem LD (2017) Degradation of trace organic contaminants by a membrane distillation—enzymatic bioreactor. Applied Sciences 7 (9): 879-894
  53. Multer K, Hollert H, Leusch FDL and Neale PA (2017). Development and application of a simple method to detect toxic chemicals in fruits and vegetables that can be implemented in a rudimentary laboratory setting: A proof of concept study. Food Control 73: 1023-1031
  54. Khan SJ, Deere D, Leusch FDL, Humpage A, Jenkins M, Cunliffe D, Fitzgerald SK and Stanford BD (2017) Lessons and guidance for the management of safe drinking water during extreme weather events. Environmental Science: Water Research and Technology 3(2): 262-277
  55. Melvin SD, Habener LJ, Leusch FDL and Carroll AR (2017). 1H NMR-based metabolomics reveals sub-lethal toxicity of a mixture of diabetic and lipid-regulating pharmaceuticals on amphibian larvae. Aquatic Toxicology 184: 123-132
  56. Neale PA, Leusch FDL and Escher BE (2017). Applying mixture toxicity modelling to predict bacterial bioluminescence inhibition by non-specifically acting pharmaceuticals and specifically acting antibiotics. Chemosphere 173: 387-394
  57. Ziajahromi S, Neale PA, Rintoul L and Leusch FDL (2017). Wastewater treatment plants as a pathway for microplastics: Development of a new approach to sample wastewater-based microplastics. Water Research 112: 93-99
  58. Deere D, Leusch FDL, Humpage A, Cunliffe D and Khan SJ (2017). Hypothetical scenario exercises to improve planning and readiness for drinking water quality management during extreme weather events. Water Research 111: 100-108
  59. Leusch FDL, Neale PA, Hebert A, Scheurer M and Schriks MCM (2017). Analysis of the sensitivity of in vitro bioassays for androgenic, progestagenic, glucocorticoid, thyroid and estrogenic activity: Suitability for drinking and environmental waters. Environment International 99: 120-130
  60. Allan HL, van de Merwe JP, Finlayson KA, O’Brien JW, Mueller JF and Leusch FDL (2017) Analysis of sugarcane herbicides in marine turtle nesting areas and assessment of risk using in vitro toxicity assays. Chemosphere 185: 656-664
  61. Scott PD, Coleman HM, Colville A, Lim R, Matthews B, McDonald JA, Miranda A, Neale PA, Nugegoda D, Tremblay LA and Leusch FDL (2017).  Assessing the potential for trace organic contaminants commonly found in Australian rivers to induce vitellogenin in the native rainbowfish (Melanotaenia fluviatilis) and the introduced mosquitofish (Gambusia holbrooki). Aquatic Toxicology 185: 105-120
  62. Ziajahromi S, Neale PA, Leusch FDL (2016). Wastewater treatment plant effluent as a source of microplastics: review of the fate, chemical interactions and potential risks to aquatic organisms. Water Science & Technology 74: 2253-2269
  63. Brockmeier EK, Scott PD, Denslow ND and Leusch FDL (2016) Transcriptomic and physiological changes in Eastern Mosquitofish (Gambusia holbrooki) after exposure to progestins and anti-progestagens. Aquatic Toxicology 179: 8-17.
  64. Finlayson KA, Leusch FDL and van de Merwe JP (2016). The current state and future directions of marine turtle toxicology research. Environment International 64: 113-123.
  65. Ashe B, Nguyen LN, Hai FI, Lee DJ, van de Merwe JP, Leusch FDL, Price WE, Nghiem LD (2016) Impacts of redox-mediator type on trace organic contaminants degradation by laccase: Degradation efficiency, laccase stability and effluent toxicity. International Biodeterioration and Biodegradation 113, 169-176.
  66. Melvin S.D, Leusch F (2016). Removal of trace organic contaminants from domestic wastewater: A meta-analysis comparison of sewage treatment technologies. Environment International, 92-93, 183 188.
  67. Lanctot C, Wilson S, Fabbro L, Leusch F, Melvin SD (2016). Comparative sensitivity of aquatic invertebrate and vertebrate species to wastewater from an operational coal mine in central Queensland, Australia. Ecotoxicology and Environmental Safety, 129, 1 9.
  68. Melvin S.D, Lanctot C, van de Merwe J, Leusch F (2016). Altered bioenergetics and developmental effects in striped marsh frog (Limnodynastes peronii) tadpoles exposed to UV treated sewage. Aquatic Toxicology, 175, 30 38.
  69. King OC, van de Merwe JP, Mcdonald JA and Leusch FD (2016). Concentrations of levonorgestrel and ethinylestradiol in wastewater effluents: Is the progestin also cause for concern? Environmental Toxicology and Chemistry 35(6): 1378-1385.
  70. Lanctot C, Melvin SD, Fabbro L, Leusch F, Wilson S (2016). Effects of coal mine wastewater on locomotor and non-locomotor activities of empire gudgeons (Hypseleotris compressa). Ecotoxicology and Environmental Safety, 127, 36 42.
  71. Lanctot C, Bennett W, Wilson S, Fabbro L, Leusch F, Melvin SD (2016). Behaviour, development and metal accumulation in striped marsh frog tadpoles (Limnodynastes peronii) exposed to coal mine wastewater. Aquatic Toxicology, 173, 218 227.
  72. Lanctot C, Melvin SD, Leusch F, Wilson S, Fabbro L (2016). Locomotor and behavioural responses of empire gudgeons (Hypseleotris compressa) exposed to coal mine wastewater. Chemosphere, 144, 1560 1566.
  73. Nguyen LN, van de Merwe J, Hai FI, Leusch FDL, Kang J, Price WE, Roddick F, Magram SF and Nghiem LD (2016). Laccase – syringaldehyde (SA) – mediated degradation of trace organic contaminants (TrOCs) in an enzymatic membrane reaction (EMR): Removal efficiency and effluent toxicity. Bioresource Technology 200: 477-484.
  74. Khan SJ, Deere D, Leusch FDL, Humpage A, Jenkins M and Cunliffe D (2015). Extreme weather events: Should drinking water quality management systems adapt to changing risk profiles? Water Research 85: 124-136
  75. Mehinto AC, Jia A, Snyder SA, Jayasinghe BS, Denslow ND, Crago J, Schlenk D, Menzie C, Westerheide SD, Leusch FDL and Maruya KA (2015). Interlaboratory comparison of in vitro bioassays for screening of endocrine active chemicals in recycled water. Water Research 83: 303-309.
  76. Escher BI, Neale PA and Leusch FDL (2015). Effect-based trigger values for in vitro bioassays: Reading across from existing water quality guideline values. Water Research 81: 137-141
  77. Prochazka E, Escher BI, Plewa MJ and Leusch FDL (2015). In vitro cytotoxicity and adaptive stress response to selected haloacetic acid and halobenzoquinone water disinfection byproducts. Chemical Research in Toxicology 28: 2059-2068.
  78. Phan HV, Hai FI, McDonald JA, Khan SJ, van de Merwe JP, Leusch FDL, Zhang R, Price WE, Broeckmann A, Nghiem LD (2015). Impact of hazardous events on the removal of nutrients and trace organic contaminants by an anoxic-aerobic membrane bioreactor receiving real wastewater. Bioresource Technology 192: 192-201
  79. Jia A, Escher BI, Leusch FDL, Tang JYM, Prochazka E, Dong B, Snuder EM and Snyder SA (2015). In vitro bioassays to evaluate complex chemical mixtures in recycled water. Water Research 80: 1-11
  80. Nguyen LN, Hai FI, Price WE, Kang J, Leusch FDL, Roddick F, van de Merwe JP, Magram SF and Nghiem LD (2015). Degradation of a broad spectrum of trace organic contaminants by an enzymatic membrane reactor: Complementary role of membrane retention and enzymatic degradation. International Biodeterioration & Biodegradation 99: 115-122
  81. Leusch FDL and Snyder SA (2015). Bioanalytical tools: Half a century of application to potable reuse. Environmental Science: Water Research & Technology 1: 606-621
  82. van de Merwe JP and Leusch FDL (2015). A sensitive and high throughput bacterial luminescence assay for assessing aquatic toxicity – the BLT-Screen. Environ Sci: Processes Impacts 17(5): 947-955
  83. Neale PA and Leusch FDL (2015). Considerations when assessing antagonism in vitro: Why standardizing the agonist concentration matters. Chemosphere 135: 20-23
  84. Neale PA and Leusch FDL (2015). Understanding the implications of dissolved organic carbon when assessing antagonism in vitro: An example with an estrogen receptor assay. Chemosphere 135: 341-346
  85. Payne ME, Chapman HF, Cumming J and Leusch FDL (2015). In vitro cytotoxicity assessment of a hydraulic fracturing fluid. Environmental Chemistry 12(3): 286-292
  86. Tang JYM, Taulis M, Edebeli J, Leusch FDL, Jagals PO, Jackson G and Escher BI (2015). Chemical and bioanalytical assessment of coal seam gas associated water. Environmental Chemistry 12(3): 267-285
  87. Nguyen L, Hai FI, Price WE, Leusch FDL, Roddick F, McAdam E, Magram SF and Nghiem L (2014). Continuous biotransformation of bisphenol A and diclofenac by laccase in an enzymatic membrane reactor. International Biodeterioration & Biodegradation 95(A): 25-32
  88. Nguyen LN, Hai FI, Yang S, Kang J, Leusch FDL, Roddick F, Price WE and Nghiem LD (2014). Removal of pharmaceuticals, steroid hormones, phytoestrogens, UV-filters, industrial chemicals and pesticides by Trametes versicolor: Role of biosorption and biodegradation. International Biodeterioration & Biodegradation 88: 169-175
  89. Leusch FDL, Khan SJ, Gagnon MM, Quayle P, Trinh T, Coleman H, Rawson C, Chapman HF, Blair P, Nice H and Reitsema T (2014). Assessment of wastewater and recycled water quality: A comparison of lines of evidence from in vitro, in vivo and chemical analyses. Water Research 50: 420-431
  90. Escher BI, Allinson M, Altenburger R, Bain P, Balaguer P, Busch W, Crago J, Denslow ND, Dopp E, Hilscherova K, Humpage AR, Kumar A, Grimaldi M, Jayasinghe BS, Jarosova B, Jia A, Makarov S, Maruya KA, Medvedev A, Mehinto AC, Mendez JE, Poulsen A, Prochazka E, Richard J, Schifferli A, Schlenk D, Scholz S, Shiraishi F, Snyder S, Su G, Tang JYM, van der Burg B, van der Linden SC, Werner I, Westerheide SD, Wong CKC, Yang M, Yeung BHY, Zhang X and Leusch FDL (2014). Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays. Environmental Science & Technology 48: 1940-1956.
  91. Leusch FDL, Khan SJ, Laingam S, Prochazka E, Froscio S, Trinh T, Chapman HF, and Humpage A (2014). Assessment of the application of bioanalytical tools as surrogate measure of chemical contaminants in recycled water. Water Research 49(1): 300-315.
  92. Nguyen LN, Hai FI, Price WE, Leusch FDL, Roddick F, Ngo HH, Guo W, Magram SF and Nghiem LD (2014). The effects of mediator and granular activated carbon addition on degradation of trace organic contaminants by an enzymatic membrane reactor. Bioresource Technology 167: 169-177
  93. Nguyen L, Hai FI, Kang J, Leusch FDL, Roddick F, Magram SF, Price WE and Nghiem LD (2014). Enhancement of trace organic contaminant degradation by crude enzyme extract from Trametes versicolor culture: Effect of mediator type and concentration. Journal of the Taiwan Institute of Chemical Engineers 45: 1855-1862.
  94. Scott PD, Bartkow M, Blockwell SJ, Coleman HM, Khan SJ, Lim R, McDonald JA, Nice H, Nugegoda D, Pettigrove V, Tremblay LA, Warne MStJ and Leusch FDL (2014). A national survey of trace organic contaminants in Australian rivers. Journal of Environmental Quality 43(5): 1702-1712
  95. Scott PD, Bartkow M, Blockwell SJ, Coleman HM, Khan SJ, Lim R, McDonald JA, Nice H, Nugegoda D, Pettigrove V, Tremblay LA, Warne MStJ and Leusch FDL (2014). An assessment of endocrine activity in Australian rivers using chemical and in vitro analyses. Environmental Science and Pollution Research 21(22): 12951-12967
  96. Nguyen LN, Hai FI, Yang S, Kang J, Leusch FDL, Roddick F, Price WE and Nghiem LD (2013). Removal of trace organic contaminants by an MBR comprising a mixed culture of bacteria and white-rot fungi. Bioresource Technology 148: 234-241.
  97. Watson K, Shaw G, Leusch F and Knight N (2012). Chlorine disinfection by-products in wastewater effluent: bioassay-based assessment of toxicological impact. Water Research 46(18): 6069-6083.
  98. Leusch FDL, Middleton D and Bartkow ME (2012). Development and application of a tool to estimate the likelihood and significance of exceedances of human health-based chemical guidelines in purified recycled water. Water 39(6): 53-57.
  99. Farré MJ, Knight N, King H, Filloux E, Keller J, Gernjak W, Watson K, Leusch FDL, Bartkow M, Taylor B and Burrell P (2012). A case study of occurrence of non-regulated disinfection by-products from the Capalaba region’s distribution system. Water 39(4): 67-71.
  100. Ho L, Grasset C, Hoefel D, Dixon MB, Leusch FD, Newcombe G, Saint CP, Brookes JD (2011). Assessing granular media filtration for the removal of chemical contaminants from wastewater. Water Research 45(11): 3461-3472.
  101. Lampard J, Leusch FDL, Roiko A and Chapman HF (2010). Contaminants of concern in recycled water. Water 37(8): 54-60.
  102. Leusch FDL, De Jager C, Levi Y, Lim R, Puijker L, Sacher F, Tremblay LA, Wilson V, and Chapman HF (2010). Comparison of five in vitro bioassays to measure estrogenic activity in environmental waters. Environmental Science & Technology 44: 3853-3860.
  103. Roux A, Robillot C, Chapman HF, Leusch FDL, Hodge M, and Walker T (2010). Hazard identification, risk assessment and verification on the Western Corridor Recycled Water Project. Water Practice and Technology 5(1) doi:10.2166/wpt.2010.005
  104. Leusch FDL, Moore MR, and Chapman HF (2009). Balancing the budget of environmental estrogen exposure – the contribution of recycled water. Water Science & Technology 60(4): 1003-1012.
  105. Kennedy K, Macova M, Leusch FDL, Bartkow ME, Hawker DW, Zhao B, Denison MS, and Mueller JF (2009). Assessing indoor air exposures using passive sampling with bioanalytical methods for estrogenicity and aryl hydrocarbon receptor activity. Analytical and Bioanalytical Chemistry 394: 1413-1421.
  106. Tan BLL, Hawker DW, Mueller JF, Leusch FDL, Tremblay LA, and Chapman HF (2007). Modelling of the fate of selected endocrine disruptors in a municipal wastewater treatment plant in South East Queensland, Australia. Chemosphere 69: 644-654.
  107. Tan BLL, Hawker DW, Mueller JF, Leusch FDL, Tremblay LA, and Chapman HF (2007). Comprehensive study of endocrine disrupting compounds using grab and passive sampling at selected wastewater treatment plants in South East Queensland, Australia. Environment International 33: 654-669.
  108. Chapman HF and Leusch F (2006). Water Recycling: Endocrine Disrupting Compounds. Water 33(6): 61-63.
  109. Bandelj E, van den Heuvel MR, Leusch FDL, Shannon N, Taylor S, and McCarthy LH (2006). Determination of the androgenic potency of whole effluents using mosquitofish and trout bioassays. Aquatic Toxicology. 80: 237-248.
  110. Leusch FDL, Chapman HF, van den Heuvel MR, Tan BLL, Gooneratne SR, and Tremblay LA (2006). Bioassay-derived androgenic and estrogenic activity in municipal sewage in Australia and New Zealand. Ecotoxicology and Environmental Safety 65: 403-411.
  111. van den Heuvel MR, Leusch FDL, Taylor S, Shannon N, McKague AB (2006). Assessment of the reproductive-endocrine disrupting potential of chlorine dioxide oxidation products of plant sterols. Environmental Science & Technology 40(8): 2594-2600.
  112. Leusch FDL, Chapman HF, Kay GW, Gooneratne SR, and Tremblay LA (2006). Anal fin morphology and gonadal histopathology in mosquitofish (Gambusia holbrooki) exposed to treated municipal sewage effluent. Archives of Environmental Contamination and Toxicology 50: 562-574.
  113. Leusch FDL, van den Heuvel MR, Chapman HF, Gooneratne SR, Eriksson AME, and Tremblay LA (2006). Development of methods for extraction and in vitro quantification of estrogenic and androgenic activity of wastewater samples. Comparative Biochemistry and Physiology Part C – Toxicology and Pharmacology 143:117-126.
  114. Sarmah AK, Northcott GL, Leusch FDL, and Tremblay LA (2006). A survey of endocrine disrupting chemicals (EDCs) in municipal sewage and animal waste effluents in the Waikato region of New Zealand. Science of the Total Environment 335(1-3): 98-105.
  115. Tremblay LA, Fisher P, Leusch FDL, van den Heuvel MR, Nicolas JC, Pilon A, and Balaguer P (2005). Potential of sodium fluoroacetate (1080) and fluorocitrate to bind to androgen and oestrogen receptors. Australasian Journal of Ecotoxicology 11(3): 155-162.
  116. Leusch FDL, van den Heuvel MR, Laurie AD, Chapman HF, Gooneratne SR, and Tremblay LA (2005). Quantification of vitellogenin mRNA induction in mosquitofish (Gambusia affinis) by reverse transcription real-time polymerase chain reaction (RT-PCR). Biomarkers 10(6): 429-438.
  117. Leusch FDL, Chapman HF, Koerner W, Gooneratne SR, and Tremblay LA (2005). Efficacy of an advanced sewage treatment plant in Southeast Queensland, Australia, to remove estrogenic chemicals. Environmental Science & Technology 39: 5781-5786.
  118. Tremblay LA, Fisher P, and Leusch FDL (2004). Potential of sodium monofluoroacetate (1080) and fluorocitrate to bind to estrogen receptor. Australasian Journal of Ecotoxicology 10(2): 77-83.
  119. Leusch FDL and MacLatchy DL (2003).  In vivo implants of beta-sitosterol cause reductions of reactive cholesterol pools in mitochondria isolated from gonads of male goldfish (Carassius auratus). General and Comparative Endocrinology 134(3): 255-263.
  120. Gilman CI, Leusch FDL, Breckenridge WC, and MacLatchy DL (2003).  Effects of a phytosterol mixture on male fish plasma lipoprotein fractions and testis P450scc activity. General and Comparative Endocrinology 130(2): 172-184.

Awards and travel grants

  • Fellow of the Australasian College of Toxicology and Risk Assessment (FACTRA) [since 2015]
  • Fellow of the Peter Cullen Trust [since 2015]
  • Griffith University DVC(A) Teaching Commendation [2014, 2015, 2016, 2017]
  • Best platform presentation, Division of Environmental Chemistry, 243rd National Meeting of the American Chemical Society [2012]
  • University of Queensland Postdoctoral Research Fellowship [2008]
  • Australasian Society for Ecotoxicology student travel award [2004]
  • New Zealand Foundation for Research, Science and Technology PhD scholarship [2001-2004]